Responsiveness of C neurons in rat dorsal root ganglion to 1 5 - hydroxytryptamine - induced pruritic stimuli in vivo
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چکیده
1 Responsiveness of C neurons in rat dorsal root ganglion to 1 5-hydroxytryptamine-induced pruritic stimuli in vivo 2 3 Junichi Hachisuka, Hidemasa Furue, Masutaka Furue, 4 Megumu Yoshimura 5 6 Department of Integrative Physiology, Department of Dermatology, 7 Graduate School of Medical Sciences, Kyushu University, Fukuoka 8 812-8582, and Graduate School of Health Sciences, Kumamoto Health 9 Science University, Kumamoto 861-5598, Japan 10 11 Running title: Itch-associated response of C neurons to 5-HT 12 13 14 15 Corresponding author: Dr Junichi Hachisuka, Department of Integrative Physiology, 16 Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, 17 Fukuoka 812-8582, Japan. Tel: +81-92-642-6089, Fax: +81-92-642-6093. 18 Email: [email protected] 19 20 Articles in PresS. J Neurophysiol (May 19, 2010). doi:10.1152/jn.00938.2009
منابع مشابه
Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo.
Itching is a common symptom in dermatologic diseases and causes restless scratching of the skin, which aggravates the condition. The mechanism of the itch sensation, however, is enigmatic. The present study included behavioral tests and electrophysiological recordings from rat dorsal root ganglion (DRG) neurons in vivo to analyze the response to pruritic stimuli induced by topical application o...
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